YIR-819 TFA salt
CAS No. 1883372-87-9
YIR-819 TFA salt ( YIR819 )
Catalog No. M12923 CAS No. 1883372-87-9
YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameYIR-819 TFA salt
-
NoteResearch use only, not for human use.
-
Brief DescriptionYIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM).
-
DescriptionYIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.
-
SynonymsYIR819
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1883372-87-9
-
Formula Weight606.04
-
Molecular FormulaC25H35ClF3N7O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameN1-(4-chlorophenyl)-N2-(1-(2-(2-guanidinoacetamido)ethyl)-1-azaspiro[5.5]undecan-4-yl)oxalamide TFA salt
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6.
2. Boonstra A, et al. Antivir Ther. 2012;17(4):657-67.
2. Boonstra A, et al. Antivir Ther. 2012;17(4):657-67.
molnova catalog
related products
-
Enfuvirtide
Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.
-
PF-46396
PF-46396 is aspecific small-molecule inhibitor of HIV-1 Gag maturation that interferes specifically with the cleavage of the CA/SP1 (p25) Gag precursor to the mature CA (p24) protein.
-
Tenofovir Disoproxil...
Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.